EndoPlus is a sublingual liquid containing 5-hydroxytryptophan (5-HTP) and Suntheanine® (L-theanine) in an advanced liposomal formula that allows for rapid absorption when a calming or relaxing effect is needed. Theanine has been widely studied for its ability to produce a calming effect and prevent excess stimulation. Theanine promotes a relaxed state of mental alertness without drowsiness or loss of focus. It is postulated that theanine’s calming effects are due to blocking glutamate activity, thereby dampening excessive excitatory neurotransmission. 5-HTP is included to support the production of serotonin.